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primary cell cultures

human melanocytes

Melanocytes are dendritic cells of neuro-ectodermal origin within which melanin is produced of tyrosine. The latter is passed to surrounding keratinocytes in the form of so-called melanosomes. Melanin provides for effective protection of skin against ultraviolet radiation. Melanin production is regulated through both UV radiation and melanocyte-stimulating hormone (MSH). Increased amounts of MSH, for example, are produced in concomitance with Addison’s disease, which grows manifest by intentified brownish discoloration of skin (tanning). An important role is played by melanocytes or melanocyte precursors in the following diseases: vitiligo (or white-spot disease), melanoma, dysplastic naevus, lentigo, melasma, BK-mole syndrome and albinism.

Human melanocytes
OFFER NO.PRODUCTDESCRIPTIONSPECIFICATIONPDF
111 0522HMEL-FHuman melanocytes, foreskinVital, 5 × 105cells/flaskdownload
121 0522HMEL-FHuman melanocytes, foreskinCryo, 5 × 105cells/vialdownload
Recommended standard culture media/subculturing system
OFFER NO.PRODUCTPDF
200 0502Melanocyte growth mediumdownload
204 0002 Passage kit 2