Human melanocytes

Melanocytes are dendritic cells of neuro-ectodermal origin within which melanin is produced of tyrosine. The latter is passed to surrounding keratinocytes in the form of so-called melanosomes. Melanin provides for effective protection of skin against ultraviolet radiation. Melanin production is regulated through both UV radiation and melanocyte-stimulating hormone (MSH). Increased amounts of MSH, for example, are produced in concomitance with Addison’s disease, which grows manifest by intentified brownish discoloration of skin (tanning). An important role is played by melanocytes or melanocyte precursors in the following diseases: vitiligo (or white-spot disease), melanoma, dysplastic naevus, lentigo, melasma, BK-mole syndrome and albinism.

Human melanocytes
OFFER NO PRODUCT DESCRIPTION SPECIFICS DETAILS
111 0522 HMEL-F Human melanocytes, foreskin Vital, 5 × 105 cells/flask
121 0522 HMEL-F Human melanocytes, foreskin Cryo, 5 × 105 cells/vial
Recommended standard culture media/subculturing system
OFFER NO PRODUCT DETAILS
200 0502 Melanocyte growth medium
204 0002 Passage kit 2
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